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In trans hydrolysis of carrier protein-bound acyl intermediates by CitA during citrinin biosynthesis
Polyketide synthases (PKSs) have several known editing mechanisms to ensure that non-productive intermediates are removed from the acyl carrier protein (ACP). We demonstrate that CitA, a putative hydrolase in the citrinin biosynthetic gene cluster, removes ACP-bound acyl intermediates. We propose th...
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| Publicado no: | Chem Commun (Camb) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5822715/ https://ncbi.nlm.nih.gov/pubmed/29189834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc07079a |
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