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Sensory domain contraction in histidine kinase CitA triggers transmembrane signaling in the membrane-bound sensor

Bacteria use membrane-integral sensor histidine kinases (HK) to perceive stimuli and transduce signals from the environment to the cytosol. Information on how the signal is transmitted across the membrane by HKs is still scarce. Combining both liquid- and solid-state NMR, we demonstrate that structu...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Salvi, Michele, Schomburg, Benjamin, Giller, Karin, Graf, Sabrina, Unden, Gottfried, Becker, Stefan, Lange, Adam, Griesinger, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373367/
https://ncbi.nlm.nih.gov/pubmed/28265100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620286114
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