Sensory domain contraction in histidine kinase CitA triggers transmembrane signaling in the membrane-bound sensor

Bacteria use membrane-integral sensor histidine kinases (HK) to perceive stimuli and transduce signals from the environment to the cytosol. Information on how the signal is transmitted across the membrane by HKs is still scarce. Combining both liquid- and solid-state NMR, we demonstrate that structu...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Salvi, Michele, Schomburg, Benjamin, Giller, Karin, Graf, Sabrina, Unden, Gottfried, Becker, Stefan, Lange, Adam, Griesinger, Christian
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2017
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373367/
https://ncbi.nlm.nih.gov/pubmed/28265100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620286114
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