Sensory domain contraction in histidine kinase CitA triggers transmembrane signaling in the membrane-bound sensor

Bacteria use membrane-integral sensor histidine kinases (HK) to perceive stimuli and transduce signals from the environment to the cytosol. Information on how the signal is transmitted across the membrane by HKs is still scarce. Combining both liquid- and solid-state NMR, we demonstrate that structu...

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發表在:Proc Natl Acad Sci U S A
Main Authors: Salvi, Michele, Schomburg, Benjamin, Giller, Karin, Graf, Sabrina, Unden, Gottfried, Becker, Stefan, Lange, Adam, Griesinger, Christian
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2017
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373367/
https://ncbi.nlm.nih.gov/pubmed/28265100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620286114
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