Jjj1 Is a Negative Regulator of Pdr1-Mediated Fluconazole Resistance in Candida glabrata

The high prevalence of fluconazole resistance among clinical isolates of Candida glabrata has greatly hampered the utility of fluconazole for the treatment of invasive candidiasis. Fluconazole resistance in this yeast is almost exclusively due to activating mutations in the transcription factor Pdr1...

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Bibliographic Details
Published in:mSphere
Main Authors: Whaley, Sarah G., Caudle, Kelly E., Simonicova, Lucia, Zhang, Qing, Moye-Rowley, W. Scott, Rogers, P. David
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821985/
https://ncbi.nlm.nih.gov/pubmed/29507891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00466-17
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