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Jjj1 Is a Negative Regulator of Pdr1-Mediated Fluconazole Resistance in Candida glabrata

The high prevalence of fluconazole resistance among clinical isolates of Candida glabrata has greatly hampered the utility of fluconazole for the treatment of invasive candidiasis. Fluconazole resistance in this yeast is almost exclusively due to activating mutations in the transcription factor Pdr1...

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Detalhes bibliográficos
Publicado no:mSphere
Main Authors: Whaley, Sarah G., Caudle, Kelly E., Simonicova, Lucia, Zhang, Qing, Moye-Rowley, W. Scott, Rogers, P. David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821985/
https://ncbi.nlm.nih.gov/pubmed/29507891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00466-17
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