Identification of the fungal ligand triggering cytotoxic PRR-mediated NK cell killing of Cryptococcus and Candida

Natural killer (NK) cells use the activating receptor NKp30 as a microbial pattern-recognition receptor to recognize, activate cytolytic pathways, and directly kill the fungi Cryptococcus neoformans and Candida albicans. However, the fungal pathogen-associated molecular pattern (PAMP) that triggers...

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Udgivet i:Nat Commun
Main Authors: Li, Shu Shun, Ogbomo, Henry, Mansour, Michael K., Xiang, Richard F., Szabo, Lian, Munro, Fay, Mukherjee, Priyanka, Mariuzza, Roy A., Amrein, Matthias, Vyas, Jatin M., Robbins, Stephen M., Mody, Christopher H.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821813/
https://ncbi.nlm.nih.gov/pubmed/29467448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03014-4
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