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Differential Expression of CD8+ T Cell Cytotoxic Effector Molecules in Blood and Gastrointestinal Mucosa in HIV-1 Infection()

We previously reported that CD8(+) T-cells in human gastrointestinal mucosa exhibit reduced perforin expression and weak or impaired cytotoxic capacity compared to their counterparts in blood. Nevertheless, these cells degranulate and express cytokines and chemokines in response to cognate antigen....

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Foilsithe in:J Immunol
Main Authors: Kiniry, Brenna E., Hunt, Peter W., Hecht, Frederick M., Somsouk, Ma, Deeks, Steven G., Shacklett, Barbara L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821568/
https://ncbi.nlm.nih.gov/pubmed/29352005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701532
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