Dissection of affinity captured LINE-1 macromolecular complexes

Long Interspersed Nuclear Element-1 (LINE-1, L1) is a mobile genetic element active in human genomes. L1-encoded ORF1 and ORF2 proteins bind L1 RNAs, forming ribonucleoproteins (RNPs). These RNPs interact with diverse host proteins, some repressive and others required for the L1 lifecycle. Using dif...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Taylor, Martin S, Altukhov, Ilya, Molloy, Kelly R, Mita, Paolo, Jiang, Hua, Adney, Emily M, Wudzinska, Aleksandra, Badri, Sana, Ischenko, Dmitry, Eng, George, Burns, Kathleen H, Fenyö, David, Chait, Brian T, Alexeev, Dmitry, Rout, Michael P, Boeke, Jef D, LaCava, John
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2018
Gaiak:
Biochemistry and Chemical Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821459/
https://ncbi.nlm.nih.gov/pubmed/29309035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.30094
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