Affinity proteomics reveals human host factors implicated in discrete stages of LINE-1 retrotransposition

LINE-1s are active human DNA parasites that are agents of genome dynamics in evolution and disease. These streamlined elements require host factors to complete their lifecycles, whereas hosts have developed mechanisms to combat retrotransposition’s mutagenic effects. As such, endogenous L1 expressio...

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Detalhes bibliográficos
Main Authors: Taylor, Martin S., LaCava, John, Mita, Paolo, Molloy, Kelly R., Huang, Cheng Ran Lisa, Li, Donghui, Adney, Emily M., Jiang, Hua, Burns, Kathleen H., Chait, Brian T., Rout, Michael P., Boeke, Jef D., Dai, Lixin
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904357/
https://ncbi.nlm.nih.gov/pubmed/24267889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.10.021
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