Comparison of the pharmacokinetics and pharmacodynamics of single-dose tenofovir vaginal film and gel formulation (FAME-05)

OBJECTIVE: While pre-exposure prophylaxis with oral tenofovir (TFV) disoproxil fumarate/emtricitabine reduces HIV acquisition rates, poor adherence to and acceptability of daily vaginal gels has led to development of vaginal film formulations to improve adherence and, potentially, enable episodic us...

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Publicado en:J Acquir Immune Defic Syndr
Autores principales: Robinson, Jennifer A., Marzinke, Mark A., Fuchs, Edward J., Bakshi, Rahul P., Spiegel, Hans M. L., Coleman, Jenell S., Rohan, Lisa C., Hendrix, Craig W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821271/
https://ncbi.nlm.nih.gov/pubmed/29135651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001587
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