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PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis
T cell non-Hodgkin lymphomas (T-NHLs) represent a heterogeneous group of highly aggressive malignancies with poor clinical outcomes1. T-NHLs originate from peripheral T lymphocytes and are frequently characterized by genetic gain-of-function variants in T cell antigen receptor (TCR) signalling molec...
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| Udgivet i: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5821214/ https://ncbi.nlm.nih.gov/pubmed/29143824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature24649 |
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