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Impairment of protein degradation and proteasome function in hereditary neuropathies
In several neurodegenerative diseases in which misfolded proteins accumulate there is impairment of the ubiquitin proteasome system (UPS). We tested if a similar disruption of proteostasis occurs in hereditary peripheral neuropathies. In sciatic nerves from mouse models of two human neuropathies, My...
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| Publicado no: | Glia |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5821146/ https://ncbi.nlm.nih.gov/pubmed/29076578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23251 |
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