Effect of early embryonic deletion of huntingtin from pyramidal neurons on the development and long-term survival of neurons in cerebral cortex and striatum

We evaluated the impact of early embryonic deletion of huntingtin (htt) from pyramidal neurons on cortical development, cortical neuron survival and motor behavior, using a cre-loxP strategy to inactivate the mouse htt gene (Hdh) in emx1-expressing cell lineages. Western blot confirmed substantial h...

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Detaylı Bibliyografya
Yayımlandı:Neurobiol Dis
Asıl Yazarlar: Dragatsis, I., Dietrich, P., Ren, H., Deng, Y.P., Del Mar, N, Wang, H.B., Johnson, I.M., Jones, K.R., Reiner, A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821111/
https://ncbi.nlm.nih.gov/pubmed/29274742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.12.015
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