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Effect of Varying Doses of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Exposure Among Patients With Peanut Sensitivity: A Randomized Clinical Trial

IMPORTANCE: Epicutaneous immunotherapy may have potential for treating peanut allergy but has been assessed only in preclinical and early human trials. OBJECTIVE: To determine the optimal dose, adverse events (AEs), and efficacy of a peanut patch for peanut allergy treatment. DESIGN, SETTING, AND PA...

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Detalhes bibliográficos
Publicado no:JAMA
Main Authors: Sampson, Hugh A., Shreffler, Wayne G., Yang, William H., Sussman, Gordon L., Brown-Whitehorn, Terri F., Nadeau, Kari C., Cheema, Amarjit S., Leonard, Stephanie A., Pongracic, Jacqueline A., Sauvage-Delebarre, Christine, Assa’ad, Amal H., de Blay, Frederic, Bird, J. Andrew, Tilles, Stephen A., Boralevi, Franck, Bourrier, Thierry, Hébert, Jacques, Green, Todd D., Gerth van Wijk, Roy, Knulst, André C., Kanny, Gisèle, Schneider, Lynda C., Kowalski, Marek L., Dupont, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820709/
https://ncbi.nlm.nih.gov/pubmed/29136445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2017.16591
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