Intact skin and not stripped skin is crucial for the safety and efficacy of peanut epicutaneous immunotherapy (EPIT) in mice

BACKGROUND: Epicutaneous immunotherapy (EPIT) on intact skin with an epicutaneous delivery system has already been used in preclinical and clinical studies. In epicutaneous vaccination and immunotherapy, the stripping of skin before application of the allergen is suggested to facilitate the passage...

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Bibliografiske detaljer
Main Authors: Mondoulet, Lucie, Dioszeghy, Vincent, Puteaux, Emilie, Ligouis, Mélanie, Dhelft, Véronique, Letourneur, Franck, Dupont, Christophe, Benhamou, Pierre-Henri
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542018/
https://ncbi.nlm.nih.gov/pubmed/23140259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-7022-2-22
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