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Orthogonality and Burdens of Heterologous AND Gate Gene Circuits in E. coli

[Image: see text] Synthetic biology approaches commonly introduce heterologous gene networks into a host to predictably program cells, with the expectation of the synthetic network being orthogonal to the host background. However, introduced circuits may interfere with the host’s physiology, either...

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Bibliographische Detailangaben
Veröffentlicht in:ACS Synth Biol
Hauptverfasser: Liu, Qijun, Schumacher, Jörg, Wan, Xinyi, Lou, Chunbo, Wang, Baojun
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2017
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820654/
https://ncbi.nlm.nih.gov/pubmed/29240998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssynbio.7b00328
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