Pentose Phosphate Shunt Modulates Reactive Oxygen Species and Nitric Oxide Production Controlling Trypanosoma cruzi in Macrophages

Metabolism provides substrates for reactive oxygen species (ROS) and nitric oxide (NO) generation, which are a part of the macrophage (Mφ) anti-microbial response. Mφs infected with Trypanosoma cruzi (Tc) produce insufficient levels of oxidative species and lower levels of glycolysis compared to cla...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Koo, Sue-jie, Szczesny, Bartosz, Wan, Xianxiu, Putluri, Nagireddy, Garg, Nisha Jain
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820298/
https://ncbi.nlm.nih.gov/pubmed/29503646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00202
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