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Real-Time Monitoring of the Aggregation of Alzheimer’s Amyloid-β by (1)H Magic Angle Spinning NMR Spectroscopy
Proton magic-angle-spinning NMR used for real-time analysis of amyloid aggregation reveals that the mechanical rotation of Aβ(1–40) monomers increases the rate of formation of aggregates, and that the increasing lag-time with peptide concentration suggests the formation of growth-incompetent species...
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| Publicado no: | Chem Commun (Camb) |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5820189/ https://ncbi.nlm.nih.gov/pubmed/29411841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc00167g |
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