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A novel mode for transcription inhibition mediated by PNA-induced R-loops with a model in vitro system
The selective inhibition of transcription of a chosen gene by an artificial agent has numerous applications. Usually, these agents are designed to bind a specific nucleotide sequence in the promoter or within the transcribed region of the chosen gene. However, since optimal binding sites might not e...
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| Veröffentlicht in: | Biochim Biophys Acta |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5820110/ https://ncbi.nlm.nih.gov/pubmed/29357316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2017.12.008 |
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