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Fanconi anemia core complex-dependent HES1 mono-ubiquitination regulates its transcriptional activity

OBJECTIVE: The Hairy Enhancer of Split 1 (HES1) is a transcriptional repressor that regulates cellular proliferation and differentiation during development. We previously found an interaction between HES1 and Fanconi anemia (FA) proteins. FA is a hematological and developmental disorder caused by mu...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Res Notes
Hauptverfasser: Tremblay, Cédric S., Huang, Feng Fei, Lévesque, Georges, Carreau, Madeleine
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5819684/
https://ncbi.nlm.nih.gov/pubmed/29463306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-018-3243-7
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