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Motile cilia of human airway epithelia contain hedgehog signaling components that mediate noncanonical hedgehog signaling
Differentiated airway epithelia produce sonic hedgehog (SHH), which is found in the thin layer of liquid covering the airway surface. Although previous studies showed that vertebrate HH signaling requires primary cilia, as airway epithelia mature, the cells lose primary cilia and produce hundreds of...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5819449/ https://ncbi.nlm.nih.gov/pubmed/29358407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719177115 |
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