Motile cilia of human airway epithelia contain hedgehog signaling components that mediate noncanonical hedgehog signaling

Differentiated airway epithelia produce sonic hedgehog (SHH), which is found in the thin layer of liquid covering the airway surface. Although previous studies showed that vertebrate HH signaling requires primary cilia, as airway epithelia mature, the cells lose primary cilia and produce hundreds of...

詳細記述

保存先:
書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Mao, Suifang, Shah, Alok S., Moninger, Thomas O., Ostedgaard, Lynda S., Lu, Lin, Tang, Xiao Xiao, Thornell, Ian M., Reznikov, Leah R., Ernst, Sarah E., Karp, Philip H., Tan, Ping, Keshavjee, Shaf, Abou Alaiwa, Mahmoud H., Welsh, Michael J.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2018
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5819449/
https://ncbi.nlm.nih.gov/pubmed/29358407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719177115
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