Loss of Bardet–Biedl syndrome proteins alters the morphology and function of motile cilia in airway epithelia

Mutations in a group of genes that contribute to ciliary function cause Bardet–Biedl syndrome (BBS). Most studies of BBS have focused on primary, sensory cilia. Here, we asked whether loss of BBS proteins would also affect motile cilia lining the respiratory tract. We found that BBS genes were expre...

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Библиографические подробности
Главные авторы: Shah, Alok S., Farmen, Sara L., Moninger, Thomas O., Businga, Thomas R., Andrews, Michael P., Bugge, Kevin, Searby, Charles C., Nishimura, Darryl, Brogden, Kim A., Kline, Joel N., Sheffield, Val C., Welsh, Michael J.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2008
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265193/
https://ncbi.nlm.nih.gov/pubmed/18299575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712327105
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