Loss of Bardet–Biedl syndrome proteins alters the morphology and function of motile cilia in airway epithelia

Mutations in a group of genes that contribute to ciliary function cause Bardet–Biedl syndrome (BBS). Most studies of BBS have focused on primary, sensory cilia. Here, we asked whether loss of BBS proteins would also affect motile cilia lining the respiratory tract. We found that BBS genes were expre...

詳細記述

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書誌詳細
主要な著者: Shah, Alok S., Farmen, Sara L., Moninger, Thomas O., Businga, Thomas R., Andrews, Michael P., Bugge, Kevin, Searby, Charles C., Nishimura, Darryl, Brogden, Kim A., Kline, Joel N., Sheffield, Val C., Welsh, Michael J.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2008
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265193/
https://ncbi.nlm.nih.gov/pubmed/18299575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712327105
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