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Extracellular vesicle budding is inhibited by redundant regulators of TAT-5 flippase localization and phospholipid asymmetry

Cells release extracellular vesicles (EVs) that mediate intercellular communication and repair damaged membranes. Despite the pleiotropic functions of EVs in vitro, their in vivo function is debated, largely because it is unclear how to induce or inhibit their formation. In particular, the mechanism...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Beer, Katharina B., Rivas-Castillo, Jennifer, Kuhn, Kenneth, Fazeli, Gholamreza, Karmann, Birgit, Nance, Jeremy F., Stigloher, Christian, Wehman, Ann M.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5819400/
https://ncbi.nlm.nih.gov/pubmed/29367422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714085115
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