Phospholipid flippases and Sfk1p, a novel regulator of phospholipid asymmetry, contribute to low permeability of the plasma membrane

Phospholipid flippase (type 4 P-type ATPase) plays a major role in the generation of phospholipid asymmetry in eukaryotic cell membranes. Loss of Lem3p-Dnf1/2p flippases leads to the exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE) on the cell surface in yeast, resulting in sens...

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Pubblicato in:Mol Biol Cell
Autori principali: Mioka, Tetsuo, Fujimura-Kamada, Konomi, Mizugaki, Nahiro, Kishimoto, Takuma, Sano, Takamitsu, Nunome, Hitoshi, Williams, David E., Andersen, Raymond J., Tanaka, Kazuma
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2018
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935070/
https://ncbi.nlm.nih.gov/pubmed/29540528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-04-0217
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