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Inositol depletion restores vesicle transport in yeast phospholipid flippase mutants.

In eukaryotic cells, type 4 P-type ATPases function as phospholipid flippases, which translocate phospholipids from the exoplasmic leaflet to the cytoplasmic leaflet of the lipid bilayer. Flippases function in the formation of transport vesicles, but the mechanism remains unknown. Here, we isolate a...

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Detalhes bibliográficos
Main Authors: Kanako Yamagami, Takaharu Yamamoto, Shota Sakai, Tetsuo Mioka, Takamitsu Sano, Yasuyuki Igarashi, Kazuma Tanaka
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2015-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC4363822?pdf=render
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