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RAPGEF5 regulates nuclear translocation of β-catenin
Canonical Wnt signaling coordinates many critical aspects of embryonic development, while dysregulated Wnt signaling contributes to common diseases, including congenital malformations and cancer. The nuclear localization of β-catenin is the defining step in pathway activation. However, despite inten...
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Publicado no: | Dev Cell |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5818985/ https://ncbi.nlm.nih.gov/pubmed/29290587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.12.001 |
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