Poly(lactic-co-glycolic acid)-loaded nanoparticles of betulinic acid for improved treatment of hepatic cancer: characterization, in vitro and in vivo evaluations

PURPOSE: The application of betulinic acid (B), a potent antineoplastic agent, is limited due to poor bioavailability, short plasma half-life and inappropriate tissue distribution. Thus, we aimed to prepare novel 50:50 poly(lactic-co-glycolic acid) (PLGA)-loaded B nanoparticles (BNP) and to compare...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Int J Nanomedicine
Auteurs principaux: Kumar, Pranesh, Singh, Ashok K, Raj, Vinit, Rai, Amit, Keshari, Amit K, Kumar, Dinesh, Maity, Biswanath, Prakash, Anand, Maiti, Sabyasachi, Saha, Sudipta
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2018
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818879/
https://ncbi.nlm.nih.gov/pubmed/29497292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S157391
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires