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Towards the design of anti-amyloid short peptide helices

A set of short peptide sequences susceptible to fibrillar aggregation produces sequneces capable of arresting elongation of amyloid fibrils. The "stop" signals are short helices customized for each individual target. Such a helix should exhibit high amphiphilicity, with differing condition...

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Detalhes bibliográficos
Publicado no:Bioinformation
Main Authors: Roterman, Irena, Banach, Mateusz, Konieczny, Leszek
Formato: Artigo
Idioma:Inglês
Publicado em: Biomedical Informatics 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818643/
https://ncbi.nlm.nih.gov/pubmed/29497253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630014001
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