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Propagation of Fibrillar Structural Forms in Proteins Stopped by Naturally Occurring Short Polypeptide Chain Fragments

Amyloids characterized by unbounded growth of fibrillar structures cause many pathological processes. Such unbounded propagation is due to the presence of a propagating hydrophobicity field around the fibril’s main axis, preventing its closure (unlike in globular proteins). Interestingly, similar fr...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Roterman, Irena, Banach, Mateusz, Konieczny, Leszek
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748646/
https://ncbi.nlm.nih.gov/pubmed/29144442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph10040089
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