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Structural analysis of the Aβ(11–42) amyloid fibril based on hydrophobicity distribution

The structure of the Aβ(11–42) amyloid available in PDB makes possible the molecular analysis of the specificity of amyloid formation. This molecule (PDB ID 2MVX) is the object of analysis. This work presents the outcome of in silico experiments involving various alternative conformations of the Aβ(...

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Publicat a:J Comput Aided Mol Des
Autors principals: Roterman, Irena, Dułak, Dawid, Gadzała, Małgorzata, Banach, Mateusz, Konieczny, Leszek
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687686/
https://ncbi.nlm.nih.gov/pubmed/31292794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-019-00209-9
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