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Roles of cytosolic phospholipase A(2)α in reproductive and systemic toxicities in 2,3,7,8-tetrachlorodibenzo-p-dioxin-exposed mice
Exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces a variety of toxicities upon binding of TCDD to aryl hydrocarbon receptor. Although this binding upregulates the synthesis of prostaglandins and their related lipid mediators via cytosolic phospholipase A(2)α (cPLA(2)α), toxicological si...
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| Publicado no: | Arch Toxicol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5818604/ https://ncbi.nlm.nih.gov/pubmed/29043426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-017-2081-z |
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