Predominant Role of Cytosolic Phospholipase A(2)α in Dioxin-induced Neonatal Hydronephrosis in Mice

Hydronephrosis is a common disease characterized by dilation of the renal pelvis and calices, resulting in loss of kidney function in the most severe cases. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces nonobstructive hydronephrosis in mouse neonates through upregulation of prostaglandin E(2) (...

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Main Authors: Yoshioka, Wataru, Kawaguchi, Tatsuya, Fujisawa, Nozomi, Aida-Yasuoka, Keiko, Shimizu, Takao, Matsumura, Fumio, Tohyama, Chiharu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918923/
https://ncbi.nlm.nih.gov/pubmed/24509627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04042
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