Roles of cytosolic phospholipase A(2)α in reproductive and systemic toxicities in 2,3,7,8-tetrachlorodibenzo-p-dioxin-exposed mice

Exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces a variety of toxicities upon binding of TCDD to aryl hydrocarbon receptor. Although this binding upregulates the synthesis of prostaglandins and their related lipid mediators via cytosolic phospholipase A(2)α (cPLA(2)α), toxicological si...

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Detaylı Bibliyografya
Yayımlandı:Arch Toxicol
Asıl Yazarlar: Fujisawa, Nozomi, Yoshioka, Wataru, Yanagisawa, Hiroyuki, Tohyama, Chiharu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Berlin Heidelberg 2017
Konular:
Molecular Toxicology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818604/
https://ncbi.nlm.nih.gov/pubmed/29043426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-017-2081-z
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