A Phase 1 Pharmacokinetic Study of Cysteamine Bitartrate Delayed-Release Capsules Following Oral Administration with Orange Juice, Water, or Omeprazole in Cystinosis

INTRODUCTION: Cystinosis is a rare, metabolic, autosomal recessive, genetic lysosomal storage disorder characterized by an accumulation of cystine in various organs and tissues. Cysteamine bitartrate (CB) is a cystine-depleting aminothiol agent approved in the United States and Europe in immediate-r...

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Bibliografische gegevens
Gepubliceerd in:Adv Ther
Hoofdauteurs: Armas, Danielle, Holt, Robert J., Confer, Nils F., Checani, Gregg C., Obaidi, Mohammad, Xie, Yuli, Brannagan, Meg
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Healthcare 2018
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818563/
https://ncbi.nlm.nih.gov/pubmed/29411268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12325-018-0661-9
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