Population pharmacokinetics and pharmacodynamics of cysteamine in nephropathic cystinosis patients

BACKGROUND: Nephropathic cystinosis is an autosomal recessive disorder resulting in an impaired transport of cystine trough the lysosomal membrane causing an accumulation of free cystine in lysosomes. The only specific treatment for nephropathic cystinosis is cysteamine bitartrate. This study was ai...

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Bibliografische gegevens
Hoofdauteurs: Bouazza, Naïm, Tréluyer, Jean-Marc, Ottolenghi, Chris, Urien, Saik, Deschenes, Georges, Ricquier, Daniel, Niaudet, Patrick, Chadefaux-Vekemans, Bernadette
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2011
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257201/
https://ncbi.nlm.nih.gov/pubmed/22195601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-6-86
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