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Population pharmacokinetics and pharmacodynamics of cysteamine in nephropathic cystinosis patients

BACKGROUND: Nephropathic cystinosis is an autosomal recessive disorder resulting in an impaired transport of cystine trough the lysosomal membrane causing an accumulation of free cystine in lysosomes. The only specific treatment for nephropathic cystinosis is cysteamine bitartrate. This study was ai...

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書誌詳細
主要な著者: Bouazza, Naïm, Tréluyer, Jean-Marc, Ottolenghi, Chris, Urien, Saik, Deschenes, Georges, Ricquier, Daniel, Niaudet, Patrick, Chadefaux-Vekemans, Bernadette
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257201/
https://ncbi.nlm.nih.gov/pubmed/22195601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-6-86
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