Population pharmacokinetics and pharmacodynamics of cysteamine in nephropathic cystinosis patients

BACKGROUND: Nephropathic cystinosis is an autosomal recessive disorder resulting in an impaired transport of cystine trough the lysosomal membrane causing an accumulation of free cystine in lysosomes. The only specific treatment for nephropathic cystinosis is cysteamine bitartrate. This study was ai...

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Detalhes bibliográficos
Main Authors: Bouazza, Naïm, Tréluyer, Jean-Marc, Ottolenghi, Chris, Urien, Saik, Deschenes, Georges, Ricquier, Daniel, Niaudet, Patrick, Chadefaux-Vekemans, Bernadette
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257201/
https://ncbi.nlm.nih.gov/pubmed/22195601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-6-86
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