A novel sustained‐release cysteamine bitartrate formulation for the treatment of cystinosis: Pharmacokinetics and safety in healthy male volunteers

The strict intake regimen of cysteamine bitartrate formulations, associated with side effects, is a concern for the treatment compliance in cystinosis therapy. Therefore, there is a need for a cysteamine formulation with an improved pharmacokinetic profile. This study investigated the pharmacokineti...

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Publicat a:Pharmacol Res Perspect
Autors principals: Berends, Cécile L., Pagan, Lisa, van Esdonk, Michiel J., Klarenbeek, Naomi B., Bergmann, Kirsten R., Moerland, Matthijs, van der Wel, Vincent, de Visser, Saco J., Büller, Hans, de Loos, Frans, de Vries, Wouter S., Waals, Hans, de Leede, Leo G. J., Burggraaf, Jacobus, Kamerling, Ingrid M. C.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992283/
https://ncbi.nlm.nih.gov/pubmed/33764642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.739
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