A novel sustained‐release cysteamine bitartrate formulation for the treatment of cystinosis: Pharmacokinetics and safety in healthy male volunteers

The strict intake regimen of cysteamine bitartrate formulations, associated with side effects, is a concern for the treatment compliance in cystinosis therapy. Therefore, there is a need for a cysteamine formulation with an improved pharmacokinetic profile. This study investigated the pharmacokineti...

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Detaylı Bibliyografya
Yayımlandı:Pharmacol Res Perspect
Asıl Yazarlar: Berends, Cécile L., Pagan, Lisa, van Esdonk, Michiel J., Klarenbeek, Naomi B., Bergmann, Kirsten R., Moerland, Matthijs, van der Wel, Vincent, de Visser, Saco J., Büller, Hans, de Loos, Frans, de Vries, Wouter S., Waals, Hans, de Leede, Leo G. J., Burggraaf, Jacobus, Kamerling, Ingrid M. C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2021
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992283/
https://ncbi.nlm.nih.gov/pubmed/33764642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.739
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