A novel sustained‐release cysteamine bitartrate formulation for the treatment of cystinosis: Pharmacokinetics and safety in healthy male volunteers

The strict intake regimen of cysteamine bitartrate formulations, associated with side effects, is a concern for the treatment compliance in cystinosis therapy. Therefore, there is a need for a cysteamine formulation with an improved pharmacokinetic profile. This study investigated the pharmacokineti...

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Pubblicato in:Pharmacol Res Perspect
Autori principali: Berends, Cécile L., Pagan, Lisa, van Esdonk, Michiel J., Klarenbeek, Naomi B., Bergmann, Kirsten R., Moerland, Matthijs, van der Wel, Vincent, de Visser, Saco J., Büller, Hans, de Loos, Frans, de Vries, Wouter S., Waals, Hans, de Leede, Leo G. J., Burggraaf, Jacobus, Kamerling, Ingrid M. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992283/
https://ncbi.nlm.nih.gov/pubmed/33764642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.739
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