Mechanisms of the action of adenine on anti‐allergic effects in mast cells

INTRODUCTION: Mast cells play an important role in allergic responses. METHODS: We herein demonstrated the mechanisms of inhibitory effect of adenine on IgE/antigen‐induced degranulation and TNF‐α release in mast cells. RESULTS: We found that these effects were dependent on the amino group of adenin...

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Detalhes bibliográficos
Publicado no:Immun Inflamm Dis
Main Authors: Hosoi, Toru, Ino, Shinsuke, Ohnishi, Fumie, Todoroki, Kenichi, Yoshii, Michiko, Kakimoto, Mai, Müller, Christa E., Ozawa, Koichiro
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818451/
https://ncbi.nlm.nih.gov/pubmed/29094492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.200
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