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Differential COMT expression and behavioral effects of COMT inhibition in male and female Wistar and alcohol preferring rats
Polymorphisms of the catechol-O-methyl transferase (COMT) gene have been associated with alcoholism, suggesting that alterations in the metabolism of catecholamines may be a critical component of the neuropathology of alcoholism. In the current experiments, the COMT inhibitor tolcapone was utilized...
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| Publicado no: | Alcohol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5818329/ https://ncbi.nlm.nih.gov/pubmed/29310047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.alcohol.2017.08.007 |
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