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Tolcapone suppresses ethanol intake in alcohol preferring rats performing a novel cued access protocol

BACKGROUND: Dopamine (DA) has been shown to play a central role in regulating motivated behavior and encoding reward. Chronic drug abuse elicits a state of hypodopaminergia in the mesocorticolimbic (MCL) system in both humans and preclinical rodent models of addiction, including those modeling alcoh...

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Publicado en:Alcohol Clin Exp Res
Main Authors: McCane, Aqilah M., Czachowski, Cristine L., Lapish, Christopher C.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260468/
https://ncbi.nlm.nih.gov/pubmed/25257296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12515
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