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Brucine suppresses ethanol intake and preference in alcohol-preferring Fawn-Hooded rats
AIM: Brucine (BRU) extracted from the seeds of Strychnos nux-vomica L is glycine receptor antagonist. We hypothesize that BRU may modify alcohol consumption by acting at glycine receptors, and evaluated the pharmacodynamic profiles and adverse effects of BRU in rat models of alcohol abuse. METHODS:...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4088279/ https://ncbi.nlm.nih.gov/pubmed/24909512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.28 |
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