The Phosphodiesterase-4 (PDE4) Inhibitor Rolipram Decreases Ethanol Seeking and Consumption in Alcohol-preferring Fawn-Hooded Rats

BACKGROUND: Alcohol dependence is a complex psychiatric disorder demanding development of novel pharmacotherapies. Since the cyclic AMP (cAMP) signaling cascade has been implicated in mediating behavioral responses to alcohol, key components in this cascade may serve as potential treatment targets....

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Wen, Rui-Ting, Zhang, Min, Qing, Wang-Jun, Liu, Qing, Wang, Wei-Ping, Lawrence, Andrew J., Zhang, Han-Ting, Liang, Jian-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335658/
https://ncbi.nlm.nih.gov/pubmed/22671516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2012.01845.x
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