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Hspb7 is a Cardioprotective Chaperone Facilitating Sarcomeric Proteostasis

Small heat shock proteins are chaperones with variable mechanisms of action. The function of cardiac family member Hspb7 is unknown, despite being identified through GWAS as a potential cardiomyopathy risk gene. We discovered that zebrafish hspb7 mutants display mild focal cardiac fibrosis and sarco...

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Bibliographische Detailangaben
Veröffentlicht in:Dev Biol
Hauptverfasser: Mercer, Emily J., Lin, Yi-Fan, Cohen-Gould, Leona, Evans, Todd
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818303/
https://ncbi.nlm.nih.gov/pubmed/29331499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2018.01.005
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