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Muscarinic acetylcholine receptors: novel opportunities for drug development

The muscarinic acetylcholine receptors are a subfamily of G protein-coupled receptors that regulate numerous fundamental functions of the central and peripheral nervous system. The past few years have witnessed unprecedented new insights into muscarinic receptor physiology pharmacology and structure...

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Détails bibliographiques
Publié dans:Nat Rev Drug Discov
Auteurs principaux: Kruse, Andrew C., Kobilka, Brian K., Gautam, Dinesh, Sexton, Patrick M., Christopoulos, Arthur, Wess, Jürgen
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818261/
https://ncbi.nlm.nih.gov/pubmed/24903776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd4295
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