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Allosteric control of human cystathionine β-synthase activity by a redox active disulfide bond

Cystathionine β-synthase (CBS) is the central enzyme in the trans-sulfuration pathway that converts homocysteine to cysteine. It is also one of the three major enzymes involved in the biogenesis of H(2)S. CBS is a complex protein with a modular three-domain architecture, the central domain of which...

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Vydáno v:J Biol Chem
Hlavní autoři: Niu, Weining, Wang, Jun, Qian, Jing, Wang, Mengying, Wu, Ping, Chen, Fei, Yan, Shasha
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818181/
https://ncbi.nlm.nih.gov/pubmed/29298893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000103
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