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The central role of DNA damage and repair in CAG repeat diseases
Diseases such as Huntington's disease and certain spinocerebellar ataxias are caused by the expansion of genomic cytosine-adenine-guanine (CAG) trinucleotide repeats beyond a specific threshold. These diseases are all characterised by neurological symptoms and central neurodegeneration, but our...
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| Pubblicato in: | Dis Model Mech |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Company of Biologists Ltd
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5818082/ https://ncbi.nlm.nih.gov/pubmed/29419417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.031930 |
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