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Nephron progenitor cell death elicits a limited compensatory response associated with interstitial expansion in the neonatal kidney

The final nephron number in an adult kidney is regulated by nephron progenitor cell availability and collecting duct branching in the fetal period. Fetal environmental perturbations that cause reductions in cell numbers in these two compartments result in low nephron endowment. Previous work has sho...

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Detalles Bibliográficos
Publicado en:Dis Model Mech
Autores principales: Muthukrishnan, Sree Deepthi, Ryzhov, Sergey, Karolak, Michele, Oxburgh, Leif
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists Ltd 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818074/
https://ncbi.nlm.nih.gov/pubmed/29196442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.030544
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