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Nephron progenitor cell death elicits a limited compensatory response associated with interstitial expansion in the neonatal kidney

The final nephron number in an adult kidney is regulated by nephron progenitor cell availability and collecting duct branching in the fetal period. Fetal environmental perturbations that cause reductions in cell numbers in these two compartments result in low nephron endowment. Previous work has sho...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Muthukrishnan, Sree Deepthi, Ryzhov, Sergey, Karolak, Michele, Oxburgh, Leif
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818074/
https://ncbi.nlm.nih.gov/pubmed/29196442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.030544
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