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Nephron progenitor cell death elicits a limited compensatory response associated with interstitial expansion in the neonatal kidney

The final nephron number in an adult kidney is regulated by nephron progenitor cell availability and collecting duct branching in the fetal period. Fetal environmental perturbations that cause reductions in cell numbers in these two compartments result in low nephron endowment. Previous work has sho...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Dis Model Mech
Prif Awduron: Muthukrishnan, Sree Deepthi, Ryzhov, Sergey, Karolak, Michele, Oxburgh, Leif
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists Ltd 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818074/
https://ncbi.nlm.nih.gov/pubmed/29196442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.030544
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